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Deep Impact of Random Amplification and Library Construction Methods on Viral Metagenomics Results
Clinical metagenomics is a broad-range agnostic detection method of pathogens, including novel microorganisms. A major limit is the low pathogen load compared to the high background of host nucleic acids. To overcome this issue, several solutions exist, such as applying a very high depth of sequenci...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915491/ https://www.ncbi.nlm.nih.gov/pubmed/33562285 http://dx.doi.org/10.3390/v13020253 |