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Structural Insights into Ligand—Receptor Interactions Involved in Biased Agonism of G-Protein Coupled Receptors

G protein-coupled receptors (GPCRs) are versatile signaling proteins that mediate complex cellular responses to hormones and neurotransmitters. Ligand directed signaling is observed when agonists, upon binding to the same receptor, trigger significantly different configuration of intracellular event...

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Detalles Bibliográficos
Autores principales: Jóźwiak, Krzysztof, Płazińska, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915493/
https://www.ncbi.nlm.nih.gov/pubmed/33561962
http://dx.doi.org/10.3390/molecules26040851