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Depletion of Cholesteryl Esters Causes Meibomian Gland Dysfunction-Like Symptoms in a Soat1-Null Mouse Model

Previous studies on ablation of several key genes of meibogenesis related to fatty acid elongation, omega oxidation, and esterification into wax esters have demonstrated that inactivation of any of them led to predicted changes in the meibum lipid profiles and caused severe abnormalities in the ocul...

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Detalles Bibliográficos
Autores principales: Butovich, Igor A., Wilkerson, Amber, Yuksel, Seher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915537/
https://www.ncbi.nlm.nih.gov/pubmed/33557318
http://dx.doi.org/10.3390/ijms22041583