Small and Simple, yet Sturdy: Conformationally Constrained Peptides with Remarkable Properties

The sheer size and vast chemical space (i.e., diverse repertoire and spatial distribution of functional groups) underlie peptides’ ability to engage in specific interactions with targets of various structures. However, the inherent flexibility of the peptide chain negatively affects binding affinity...

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Detalles Bibliográficos
Autores principales: Bozovičar, Krištof, Bratkovič, Tomaž
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915549/
https://www.ncbi.nlm.nih.gov/pubmed/33562633
http://dx.doi.org/10.3390/ijms22041611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915549/
https://www.ncbi.nlm.nih.gov/pubmed/33562633
http://dx.doi.org/10.3390/ijms22041611

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