Cargando…
Small and Simple, yet Sturdy: Conformationally Constrained Peptides with Remarkable Properties
The sheer size and vast chemical space (i.e., diverse repertoire and spatial distribution of functional groups) underlie peptides’ ability to engage in specific interactions with targets of various structures. However, the inherent flexibility of the peptide chain negatively affects binding affinity...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915549/ https://www.ncbi.nlm.nih.gov/pubmed/33562633 http://dx.doi.org/10.3390/ijms22041611 |