Polyphyllin D Shows Anticancer Effect through a Selective Inhibition of Src Homology Region 2-Containing Protein Tyrosine Phosphatase-2 (SHP2)

Natural products have continued to offer tremendous opportunities for drug development, as they have long been used in traditional medicinal systems. SHP2 has served as an anticancer target. To identify novel SHP2 inhibitors with potential anticancer activity, we screened a library containing 658 na...

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Detalles Bibliográficos
Autores principales: Kwon, Se Jeong, Ahn, Dohee, Yang, Hyun-Mo, Kang, Hyo Jin, Chung, Sang J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915588/
https://www.ncbi.nlm.nih.gov/pubmed/33562835
http://dx.doi.org/10.3390/molecules26040848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915588/
https://www.ncbi.nlm.nih.gov/pubmed/33562835
http://dx.doi.org/10.3390/molecules26040848

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