Multifunctional Isosteric Pyridine Analogs-Based 2-Aminothiazole: Design, Synthesis, and Potential Phosphodiesterase-5 Inhibitory Activity

The elaboration of new small molecules that target phosphodiesterase enzymes (PDEs), especially those of type 5 (PDE5), is an interesting and emerging topic nowadays. A new series of heterocycle-based aminothiazoles were designed and synthesized from the key intermediate, 3-oxo-N-(thiazol-2-yl)butan...

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Detalles Bibliográficos
Autores principales: Hussein, Abdel Haleem M., Khames, Ahmed A., El-Adasy, Abu-Bakr A., Atalla, Ahmed A., Abdel-Rady, Mohamed, Hassan, Mohamed I. A., Abou-Salim, Mahrous A., Elshaier, Yaseen A. M. M., Barakat, Assem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915674/
https://www.ncbi.nlm.nih.gov/pubmed/33572094
http://dx.doi.org/10.3390/molecules26040902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915674/
https://www.ncbi.nlm.nih.gov/pubmed/33572094
http://dx.doi.org/10.3390/molecules26040902

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