Pan-Cancer Analysis Shows TP53 Mutations Modulate the Association of NOX4 with Genetic Programs of Cancer Progression and Clinical Outcome

Previously, we have shown TGF-β-induced NOX4 expression is involved in the epithelial-to-mesenchymal transition (EMT), a process critical for cancer metastasis, and that wild-type (WT) and mutant (Mut) p53 have divergent effects on TGF-β induction of NOX4: WT-p53 suppresses whereas Mut-p53 augments...

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Detalles Bibliográficos
Autores principales: Ma, Wei Feng, Boudreau, Howard E., Leto, Thomas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915715/
https://www.ncbi.nlm.nih.gov/pubmed/33557266
http://dx.doi.org/10.3390/antiox10020235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915715/
https://www.ncbi.nlm.nih.gov/pubmed/33557266
http://dx.doi.org/10.3390/antiox10020235

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