In Silico Investigation of the New UK (B.1.1.7) and South African (501Y.V2) SARS-CoV-2 Variants with a Focus at the ACE2–Spike RBD Interface

SARS-CoV-2 exploits angiotensin-converting enzyme 2 (ACE2) as a receptor to invade cells. It has been reported that the UK and South African strains may have higher transmission capabilities, eventually in part due to amino acid substitutions on the SARS-CoV-2 Spike protein. The pathogenicity seems...

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Detalles Bibliográficos
Autores principales: Villoutreix, Bruno O., Calvez, Vincent, Marcelin, Anne-Geneviève, Khatib, Abdel-Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915722/
https://www.ncbi.nlm.nih.gov/pubmed/33567580
http://dx.doi.org/10.3390/ijms22041695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915722/
https://www.ncbi.nlm.nih.gov/pubmed/33567580
http://dx.doi.org/10.3390/ijms22041695

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