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In Silico Investigation of the New UK (B.1.1.7) and South African (501Y.V2) SARS-CoV-2 Variants with a Focus at the ACE2–Spike RBD Interface
SARS-CoV-2 exploits angiotensin-converting enzyme 2 (ACE2) as a receptor to invade cells. It has been reported that the UK and South African strains may have higher transmission capabilities, eventually in part due to amino acid substitutions on the SARS-CoV-2 Spike protein. The pathogenicity seems...
Autores principales: | Villoutreix, Bruno O., Calvez, Vincent, Marcelin, Anne-Geneviève, Khatib, Abdel-Majid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915722/ https://www.ncbi.nlm.nih.gov/pubmed/33567580 http://dx.doi.org/10.3390/ijms22041695 |
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