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Synthesis and Biological Evaluation of Oleanolic Acid Derivatives as Selective Vascular Endothelial Growth Factor Promoter i-Motif Ligands

Vascular endothelial growth factor (VEGF) is an angiogenic growth factor and plays a key role in tumor progression. The C-rich DNA sequence of VEGF promoter can form i-motif structure, which is a potential target for the development of novel anticancer agents. However, there is a limited number of c...

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Detalles Bibliográficos
Autores principales: Zeng, Huang, Kang, Shuangshuang, Zhang, Yu, Liu, Ke, Yu, Qian, Li, Ding, An, Lin-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915724/
https://www.ncbi.nlm.nih.gov/pubmed/33567767
http://dx.doi.org/10.3390/ijms22041711