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Screening of Yeast Display Libraries of Enzymatically Treated Peptides to Discover Macrocyclic Peptide Ligands

We present the construction and screening of yeast display libraries of post-translationally modified peptides wherein site-selective enzymatic treatment of linear peptides is achieved using bacterial transglutaminase. To this end, we developed two alternative routes, namely (i) yeast display of lin...

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Detalles Bibliográficos
Autores principales: Bowen, John, Schneible, John, Bacon, Kaitlyn, Labar, Collin, Menegatti, Stefano, Rao, Balaji M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915732/
https://www.ncbi.nlm.nih.gov/pubmed/33562883
http://dx.doi.org/10.3390/ijms22041634