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Phosphoproteomic Landscape of AML Cells Treated with the ATP-Competitive CK2 Inhibitor CX-4945

Casein kinase 2 (CK2) regulates a plethora of proteins with pivotal roles in solid and hematological neoplasia. Particularly, in acute myeloid leukemia (AML) CK2 has been pointed as an attractive therapeutic target and prognostic marker. Here, we explored the impact of CK2 inhibition over the phosph...

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Detalles Bibliográficos
Autores principales: Rosales, Mauro, Rodríguez-Ulloa, Arielis, Besada, Vladimir, Ramón, Ailyn C., Pérez, George V., Ramos, Yassel, Guirola, Osmany, González, Luis J., Zettl, Katharina, Wiśniewski, Jacek R., Perera, Yasser, Perea, Silvio E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915770/
https://www.ncbi.nlm.nih.gov/pubmed/33562780
http://dx.doi.org/10.3390/cells10020338