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Transgenic Mice Overexpressing PG1 Display Corneal Opacity and Severe Inflammation in the Eye

Antimicrobial peptides (AMPs) are of interest as alternatives to antibiotics or immunomodulators. We generated and characterized the phenotypes of transgenic mice overexpressing protegrin 1 (PG1), a potent porcine cathelicidin. No obvious differences were observed between PG1 transgenic and wild-typ...

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Detalles Bibliográficos
Autores principales: Choi, Min-Kyeung, Le, Minh Thong, Cho, Hye-Sun, Lee, Juyoung, Jeon, Hyoim, Cha, Se-Yeoun, Na, Manheum, Chun, Taehoon, Kim, Jin-Hoi, Song, Hyuk, Park, Chankyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915784/
https://www.ncbi.nlm.nih.gov/pubmed/33557346
http://dx.doi.org/10.3390/ijms22041586