Anticancer Therapy with HDAC Inhibitors: Mechanism-Based Combination Strategies and Future Perspectives

SIMPLE SUMMARY: Beyond mutations, epigenetic changes have been described as drivers for cancer as well. While leaving the overall DNA structure intact, they can be responsible for tumor malignancy by mediating the transcriptional upregulation of oncogenes. This provides the basis for “epigenetic the...

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Detalles Bibliográficos
Autores principales: Jenke, Robert, Reßing, Nina, Hansen, Finn K., Aigner, Achim, Büch, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915831/
https://www.ncbi.nlm.nih.gov/pubmed/33562653
http://dx.doi.org/10.3390/cancers13040634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915831/
https://www.ncbi.nlm.nih.gov/pubmed/33562653
http://dx.doi.org/10.3390/cancers13040634

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