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Entropic Competition between Supercoiled and Torsionally Relaxed Chromatin Fibers Drives Loop Extrusion through Pseudo-Topologically Bound Cohesin

SIMPLE SUMMARY: Chromatin dynamics and chromatin structure are a two-way relationship governed by polymer physics and active biological processes. Thanks to the research in the field of computational biology and modeling, computer simulations became indispensable in studying these complex relationsh...

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Detalles Bibliográficos
Autores principales: Rusková, Renáta, Račko, Dušan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915857/
https://www.ncbi.nlm.nih.gov/pubmed/33562371
http://dx.doi.org/10.3390/biology10020130