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Preclinical Evaluation of [(18)F]FACH in Healthy Mice and Piglets: An (18)F-Labeled Ligand for Imaging of Monocarboxylate Transporters with PET

The expression of monocarboxylate transporters (MCTs) is linked to pathophysiological changes in diseases, including cancer, such that MCTs could potentially serve as diagnostic markers or therapeutic targets. We recently developed [(18)F]FACH as a radiotracer for non-invasive molecular imaging of M...

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Detalles Bibliográficos
Autores principales: Gündel, Daniel, Sadeghzadeh, Masoud, Deuther-Conrad, Winnie, Wenzel, Barbara, Cumming, Paul, Toussaint, Magali, Ludwig, Friedrich-Alexander, Moldovan, Rareş-Petru, Kranz, Mathias, Teodoro, Rodrigo, Sattler, Bernhard, Sabri, Osama, Brust, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915902/
https://www.ncbi.nlm.nih.gov/pubmed/33562048
http://dx.doi.org/10.3390/ijms22041645