Identification of RSV Fusion Protein Interaction Domains on the Virus Receptor, Nucleolin

Nucleolin is an essential cellular receptor to human respiratory syncytial virus (RSV). Pharmacological targeting of the nucleolin RNA binding domain RBD1,2 can inhibit RSV infections in vitro and in vivo; however, the site(s) on RBD1,2 which interact with RSV are not known. We undertook a series of...

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Detalles Bibliográficos
Autores principales: Mastrangelo, Peter, Chin, Allysia A., Tan, Stephanie, Jeon, Amy H., Ackerley, Cameron A., Siu, Karen K., Lee, Jeffrey E., Hegele, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915953/
https://www.ncbi.nlm.nih.gov/pubmed/33567674
http://dx.doi.org/10.3390/v13020261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915953/
https://www.ncbi.nlm.nih.gov/pubmed/33567674
http://dx.doi.org/10.3390/v13020261

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