Hiltonol Cocktail Kills Lung Cancer Cells by Activating Cancer-Suppressors, PKR/OAS, and Restraining the Tumor Microenvironment

NSCLC (non-small cell lung cancer) is a leading cause of cancer-related deaths worldwide. Clinical trials showed that Hiltonol, a stable dsRNA representing an advanced form of polyI:C (polyinosinic-polycytidilic acid), is an adjuvant cancer-immunomodulator. However, its mechanisms of action and effe...

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Detalles Bibliográficos
Autores principales: Chang, Shu-Chun, Zhang, Bo-Xiang, Su, Emily Chia-Yu, Wu, Wei-Ciao, Hsieh, Tsung-Han, Salazar, Andres M., Lin, Yen-Kuang, Ding, Jeak Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915988/
https://www.ncbi.nlm.nih.gov/pubmed/33562773
http://dx.doi.org/10.3390/ijms22041626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915988/
https://www.ncbi.nlm.nih.gov/pubmed/33562773
http://dx.doi.org/10.3390/ijms22041626

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