A Novel Triplet-Primed PCR Assay to Detect the Full Range of Trinucleotide CAG Repeats in the Huntingtin Gene (HTT)

The expanded CAG repeat number in HTT gene causes Huntington disease (HD), which is a severe, dominant neurodegenerative illness. The accurate determination of the expanded allele size is crucial to confirm the genetic status in symptomatic and presymptomatic at-risk subjects and avoid genetic polym...

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Detalles Bibliográficos
Autores principales: De Luca, Alessandro, Morella, Annunziata, Consoli, Federica, Fanelli, Sergio, Thibert, Julie R., Statt, Sarah, Latham, Gary J., Squitieri, Ferdinando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916029/
https://www.ncbi.nlm.nih.gov/pubmed/33567536
http://dx.doi.org/10.3390/ijms22041689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916029/
https://www.ncbi.nlm.nih.gov/pubmed/33567536
http://dx.doi.org/10.3390/ijms22041689

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