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Distinct Features of Germinal Center Reactions in Macaques Infected by SIV or Vaccinated with a T-Dependent Model Antigen

B-cell follicles constitute large reservoirs of infectious HIV/SIV associated to follicular dendritic cells and infecting follicular helper (T(FH)) and regulatory (T(FR)) T-cells in germinal centers (GCs). Thus, follicular and GC B-cells are persistently exposed to viral antigens. Despite recent dev...

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Detalles Bibliográficos
Autores principales: Trovato, Maria, Ibrahim, Hany M., Isnard, Stephane, Le Grand, Roger, Bosquet, Nathalie, Borhis, Gwenoline, Richard, Yolande
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916050/
https://www.ncbi.nlm.nih.gov/pubmed/33572146
http://dx.doi.org/10.3390/v13020263