Cutting Edge of the Pathogenesis of Atopic Dermatitis: Sphingomyelin Deacylase, the Enzyme Involved in Its Ceramide Deficiency, Plays a Pivotal Role

Atopic dermatitis (AD) is characterized clinically by severe dry skin and functionally by both a cutaneous barrier disruption and an impaired water-holding capacity in the stratum corneum (SC) even in the nonlesional skin. The combination of the disrupted barrier and water-holding functions in nonle...

Descripción completa

Detalles Bibliográficos
Autor principal: Imokawa, Genji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916095/
https://www.ncbi.nlm.nih.gov/pubmed/33562655
http://dx.doi.org/10.3390/ijms22041613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916095/
https://www.ncbi.nlm.nih.gov/pubmed/33562655
http://dx.doi.org/10.3390/ijms22041613

Ejemplares similares