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Tat-Endophilin A1 Fusion Protein Protects Neurons from Ischemic Damage in the Gerbil Hippocampus: A Possible Mechanism of Lipid Peroxidation and Neuroinflammation Mitigation as Well as Synaptic Plasticity

The present study explored the effects of endophilin A1 (SH3GL2) against oxidative damage brought about by H(2)O(2) in HT22 cells and ischemic damage induced upon transient forebrain ischemia in gerbils. Tat-SH3GL2 and its control protein (Control-SH3GL2) were synthesized to deliver it to the cells...

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Detalles Bibliográficos
Autores principales: Jung, Hyo Young, Kwon, Hyun Jung, Kim, Woosuk, Hwang, In Koo, Choi, Goang-Min, Chang, In Bok, Kim, Dae Won, Moon, Seung Myung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916150/
https://www.ncbi.nlm.nih.gov/pubmed/33572372
http://dx.doi.org/10.3390/cells10020357