Protein Kinase A-Mediated Septin7 Phosphorylation Disrupts Septin Filaments and Ciliogenesis

Septins are GTP-binding proteins that form heteromeric filaments for proper cell growth and migration. Among the septins, septin7 (SEPT7) is an important component of all septin filaments. Here we show that protein kinase A (PKA) phosphorylates SEPT7 at Thr197, thus disrupting septin filament dynami...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Han-Yu, Lin, Chun-Hsiang, Shen, Yi-Ru, Chen, Ting-Yu, Wang, Chia-Yih, Kuo, Pao-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916176/
https://www.ncbi.nlm.nih.gov/pubmed/33572403
http://dx.doi.org/10.3390/cells10020361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916176/
https://www.ncbi.nlm.nih.gov/pubmed/33572403
http://dx.doi.org/10.3390/cells10020361

Ejemplares similares