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Protein Kinase A-Mediated Septin7 Phosphorylation Disrupts Septin Filaments and Ciliogenesis

Septins are GTP-binding proteins that form heteromeric filaments for proper cell growth and migration. Among the septins, septin7 (SEPT7) is an important component of all septin filaments. Here we show that protein kinase A (PKA) phosphorylates SEPT7 at Thr197, thus disrupting septin filament dynami...

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Detalles Bibliográficos
Autores principales:	Wang, Han-Yu, Lin, Chun-Hsiang, Shen, Yi-Ru, Chen, Ting-Yu, Wang, Chia-Yih, Kuo, Pao-Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916176/ https://www.ncbi.nlm.nih.gov/pubmed/33572403 http://dx.doi.org/10.3390/cells10020361

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