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Identification of Novel phoP-phoQ Regulated Genes that Contribute to Polymyxin B Tolerance in Pseudomonas aeruginosa

Polymyxin B and E (colistin) are the last resorts to treat multidrug-resistant Gram-negative pathogens. Pseudomonas aeruginosa is intrinsically resistant to a variety of antibiotics. The PhoP-PhoQ two-component regulatory system contributes to the resistance to polymyxins by regulating an arnBCADTEF...

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Detalles Bibliográficos
Autores principales: Yang, Baopeng, Liu, Chang, Pan, Xiaolei, Fu, Weixin, Fan, Zheng, Jin, Yongxin, Bai, Fang, Cheng, Zhihui, Wu, Weihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916210/
https://www.ncbi.nlm.nih.gov/pubmed/33572426
http://dx.doi.org/10.3390/microorganisms9020344