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Measurement of gene amplifications related to drug resistance in Plasmodium falciparum using droplet digital PCR

BACKGROUND: Copy number variations (CNVs) of the Plasmodium falciparum multidrug resistance 1 (pfmdr1), P. falciparum plasmepsin2 (pfplasmepsin2) and P. falciparum GTP cyclohydrolase 1 (pfgch1) genes are associated with anti-malarial drug resistance in P. falciparum malaria. Droplet digital PCR (ddP...

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Detalles Bibliográficos
Autores principales: Srisutham, Suttipat, Suwannasin, Kanokon, Sugaram, Rungniran, Dondorp, Arjen M., Imwong, Mallika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916280/
https://www.ncbi.nlm.nih.gov/pubmed/33639924
http://dx.doi.org/10.1186/s12936-021-03659-5