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Macrophage migration inhibitory factor facilitates the therapeutic efficacy of mesenchymal stem cells derived exosomes in acute myocardial infarction through upregulating miR-133a-3p

BACKGROUND: Exosome transplantation is a promising cell-free therapeutic approach for the treatment of ischemic heart disease. The purpose of this study was to explore whether exosomes derived from Macrophage migration inhibitory factor (MIF) engineered umbilical cord MSCs (ucMSCs) exhibit superior...

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Detalles Bibliográficos
Autores principales: Zhu, Wenwu, Sun, Ling, Zhao, Pengcheng, Liu, Yaowu, Zhang, Jian, Zhang, Yuelin, Hong, Yimei, Zhu, Yeqian, Lu, Yao, Zhao, Wei, Chen, Xinguang, Zhang, Fengxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916292/
https://www.ncbi.nlm.nih.gov/pubmed/33639970
http://dx.doi.org/10.1186/s12951-021-00808-5