Tumor Suppressor Protein p53 and Inhibitor of Apoptosis Proteins in Colorectal Cancer—A Promising Signaling Network for Therapeutic Interventions

SIMPLE SUMMARY: Tumor suppressor 53 (p53) is a multifunctional protein that regulates cell cycle, DNA repair, apoptosis and metabolic pathways. In colorectal cancer (CRC), mutations of the gene occur in 60% of patients and are associated with a more aggressive tumor phenotype and resistance to anti-...

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Detalles Bibliográficos
Autores principales: Güllülü, Ömer, Hehlgans, Stephanie, Rödel, Claus, Fokas, Emmanouil, Rödel, Franz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916307/
https://www.ncbi.nlm.nih.gov/pubmed/33557398
http://dx.doi.org/10.3390/cancers13040624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916307/
https://www.ncbi.nlm.nih.gov/pubmed/33557398
http://dx.doi.org/10.3390/cancers13040624

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