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Post-Transcriptional Regulation of PARP7 Protein Stability Is Controlled by Androgen Signaling

Poly-ADP-ribose polymerases (PARPs) are enzymes that catalyze ADP-ribosylation and play critical roles in normal and disease settings. The PARP family member, PARP7, is a mono-ADP-ribosyltransferase that has been suggested to play a tumor suppressive role in breast, ovarian, and colorectal cancer. H...

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Detalles Bibliográficos
Autores principales: Kamata, Teddy, Yang, Chun-Song, Melhuish, Tiffany A., Frierson Jr., Henry F., Wotton, David, Paschal, Bryce M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916378/
https://www.ncbi.nlm.nih.gov/pubmed/33572475
http://dx.doi.org/10.3390/cells10020363