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Differential Action of Connexin Hemichannel and Pannexin Channel Therapeutics for Potential Treatment of Retinal Diseases

Dysregulation of retinal function in the early stages of light-induced retinal degeneration involves pannexins and connexins. These two types of proteins may contribute to channels that release ATP, leading to activation of the inflammasome pathway, spread of inflammation and retinal dysfunction. Ho...

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Detalles Bibliográficos
Autores principales: Mat Nor, Mohd N., Rupenthal, Ilva D., Green, Colin R., Acosta, Monica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916454/
https://www.ncbi.nlm.nih.gov/pubmed/33578721
http://dx.doi.org/10.3390/ijms22041755