Cargando…
Differential Action of Connexin Hemichannel and Pannexin Channel Therapeutics for Potential Treatment of Retinal Diseases
Dysregulation of retinal function in the early stages of light-induced retinal degeneration involves pannexins and connexins. These two types of proteins may contribute to channels that release ATP, leading to activation of the inflammasome pathway, spread of inflammation and retinal dysfunction. Ho...
Autores principales: | Mat Nor, Mohd N., Rupenthal, Ilva D., Green, Colin R., Acosta, Monica L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916454/ https://www.ncbi.nlm.nih.gov/pubmed/33578721 http://dx.doi.org/10.3390/ijms22041755 |
Ejemplares similares
-
Connexin therapeutics: blocking connexin hemichannel pores is distinct from blocking pannexin channels or gap junctions
por: Acosta, Monica L., et al.
Publicado: (2020) -
Xentry-Gap19 inhibits Connexin43 hemichannel opening especially during hypoxic injury
por: Coutinho, Frazer P., et al.
Publicado: (2020) -
Tonabersat Inhibits Connexin43 Hemichannel Opening and Inflammasome Activation in an In Vitro Retinal Epithelial Cell Model of Diabetic Retinopathy
por: Lyon, Heather, et al.
Publicado: (2020) -
Pannexin channel and connexin hemichannel expression in vascular function and inflammation
por: Begandt, Daniela, et al.
Publicado: (2017) -
Connexin and Pannexin hemichannels are regulated by redox potential
por: Retamal, Mauricio A.
Publicado: (2014)