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Senolytics for Cancer Therapy: Is All that Glitters Really Gold?

SIMPLE SUMMARY: Senescence is an essential component of tumor cell biology and is a primary cell stress response to therapy. While the long-term impact of senescence in cancer therapy is not yet fully understood, the use of senolytics, drugs that selectively kill senescent cells, is an area of activ...

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Detalles Bibliográficos
Autores principales: Carpenter, Valerie J., Saleh, Tareq, Gewirtz, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916462/
https://www.ncbi.nlm.nih.gov/pubmed/33578753
http://dx.doi.org/10.3390/cancers13040723