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Blocking Migration of Polymorphonuclear Myeloid-Derived Suppressor Cells Inhibits Mouse Melanoma Progression

SIMPLE SUMMARY: Myeloid-derived suppressor cells (MDSC) represent a heterogeneous myeloid cell population that is expanded in tumor bearing hosts and substantially contributes to immunosuppression, representing thereby a valuable therapeutic target. Our study analyzes polymorphonuclear (PMN) and mon...

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Detalles Bibliográficos
Autores principales: Groth, Christopher, Arpinati, Ludovica, Shaul, Merav E., Winkler, Nina, Diester, Klara, Gengenbacher, Nicolas, Weber, Rebekka, Arkhypov, Ihor, Lasser, Samantha, Petrova, Vera, Augustin, Hellmut G., Altevogt, Peter, Utikal, Jochen, Fridlender, Zvi G., Umansky, Viktor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916588/
https://www.ncbi.nlm.nih.gov/pubmed/33578808
http://dx.doi.org/10.3390/cancers13040726