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Anti-Tumor Efficiency of Perillylalcohol/β-Cyclodextrin Inclusion Complexes in a Sarcoma S180-Induced Mice Model

The low solubility and high volatility of perillyl alcohol (POH) compromise its bioavailability and potential use as chemotherapeutic drug. In this work, we have evaluated the anticancer activity of POH complexed with β-cyclodextrin (β-CD) using three complexation approaches. Molecular docking sugge...

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Detalles Bibliográficos
Autores principales: Rezende, Allan A., Santos, Rafael S., Andrade, Luciana N., Amaral, Ricardo G., Pereira, Matheus M., Bani, Cristiane, Chen, Mo, Priefer, Ronny, da Silva, Classius F., de Albuquerque Júnior, Ricardo L. C., Souto, Eliana B., Severino, Patrícia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916601/
https://www.ncbi.nlm.nih.gov/pubmed/33578857
http://dx.doi.org/10.3390/pharmaceutics13020245