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Urinary miRNA Biomarkers of Drug-Induced Kidney Injury and Their Site Specificity Within the Nephron

Drug-induced kidney injury (DIKI) is a major concern in both drug development and clinical practice. There is an unmet need for biomarkers of glomerular damage and more distal renal injury in the loop of Henle and the collecting duct (CD). A cross-laboratory program to identify and characterize urin...

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Detalles Bibliográficos
Autores principales: Chorley, Brian N, Ellinger-Ziegelbauer, Heidrun, Tackett, Michael, Simutis, Frank J, Harrill, Alison H, McDuffie, James, Atabakhsh, Elnaz, Nassirpour, Rounak, Whiteley, Laurence O, Léonard, Jean-François, Carswell, Gleta K, Harpur, Ernie, Chen, Connie L, Gautier, Jean-Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916737/
https://www.ncbi.nlm.nih.gov/pubmed/33367795
http://dx.doi.org/10.1093/toxsci/kfaa181