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Regulation of p53 by E3s
SIMPLE SUMMARY: The p53 protein is a transcription factor that initiates cell cycle arrest and apoptosis and by this counteracts tumorigenesis. Because of its anti-proliferative activity, p53 levels are usually low as the protein is rapidly degraded, unless its anti-tumoral activity is required. E3s...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916862/ https://www.ncbi.nlm.nih.gov/pubmed/33670160 http://dx.doi.org/10.3390/cancers13040745 |