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CFTR Deficiency Affects Glucose Homeostasis via Regulating GLUT4 Plasma Membrane Transportation

Cystic Fibrosis (CF) is an autosomal recessive disorder caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene. CF-related diabetes (CFRD) is one of the most prevalent comorbidities of CF. Altered glucose homeostasis has been reported in CF patients. The mechanism...

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Detalles Bibliográficos
Autores principales: Gu, Junzhong, Zhang, Weiwei, Wu, Lida, Gu, Yuchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917208/
https://www.ncbi.nlm.nih.gov/pubmed/33659254
http://dx.doi.org/10.3389/fcell.2021.630654