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Cardiac Gq Receptors and Calcineurin Activation Are Not Required for the Hypertrophic Response to Mechanical Left Ventricular Pressure Overload

RATIONALE: Gq-coupled receptors are thought to play a critical role in the induction of left ventricular hypertrophy (LVH) secondary to pressure overload, although mechano-sensitive channel activation by a variety of mechanisms has also been proposed, and the relative importance of calcineurin- and...

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Detalles Bibliográficos
Autores principales: Yu, Ze-Yan, Gong, Hutao, Wu, Jianxin, Dai, Yun, Kesteven, Scott H., Fatkin, Diane, Martinac, Boris, Graham, Robert M., Feneley, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917224/
https://www.ncbi.nlm.nih.gov/pubmed/33659256
http://dx.doi.org/10.3389/fcell.2021.639509