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Cardiac Gq Receptors and Calcineurin Activation Are Not Required for the Hypertrophic Response to Mechanical Left Ventricular Pressure Overload
RATIONALE: Gq-coupled receptors are thought to play a critical role in the induction of left ventricular hypertrophy (LVH) secondary to pressure overload, although mechano-sensitive channel activation by a variety of mechanisms has also been proposed, and the relative importance of calcineurin- and...
Autores principales: | Yu, Ze-Yan, Gong, Hutao, Wu, Jianxin, Dai, Yun, Kesteven, Scott H., Fatkin, Diane, Martinac, Boris, Graham, Robert M., Feneley, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917224/ https://www.ncbi.nlm.nih.gov/pubmed/33659256 http://dx.doi.org/10.3389/fcell.2021.639509 |
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