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Comprehensive Analysis of CD4(+) T Cell Responses to CMV pp65 Antigen Restricted by Single HLA-DR, -DQ, and -DP Allotype Within an Individual

Within an individual, six different HLA class II heterodimers are expressed co-dominantly by two alleles of HLA-DR, -DQ, and -DP loci. However, it remained unclear which HLA allotypes were used in T cell responses to a given antigen. For the measurement of the CD4(+) T cell responses restricted by a...

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Detalles Bibliográficos
Autores principales: Hyun, You-Seok, Jo, Hyeong-A, Lee, Yong-Hun, Kim, Sun-Mi, Baek, In-Cheol, Sohn, Hyun-Jung, Cho, Hyun-Il, Kim, Tai-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917246/
https://www.ncbi.nlm.nih.gov/pubmed/33658991
http://dx.doi.org/10.3389/fimmu.2020.602014