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Fatty Acid Desaturase 1 Influences Hepatic Lipid Homeostasis by Modulating the PPARα‐FGF21 Axis

The fatty acid desaturase 1 (FADS1), also known as delta‐5 desaturase (D5D), is one of the rate‐limiting enzymes involved in the desaturation and elongation cascade of polyunsaturated fatty acids (PUFAs) to generate long‐chain PUFAs (LC‐PUFAs). Reduced function of D5D and decreased hepatic FADS1 exp...

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Detalles Bibliográficos
Autores principales: Athinarayanan, Shaminie, Fan, Yang‐Yi, Wang, Xiaokun, Callaway, Evelyn, Cai, Defeng, Chalasani, Naga, Chapkin, Robert S., Liu, Wanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917273/
https://www.ncbi.nlm.nih.gov/pubmed/33681679
http://dx.doi.org/10.1002/hep4.1629