Vanillic Acid Reduces Pain-Related Behavior in Knee Osteoarthritis Rats Through the Inhibition of NLRP3 Inflammasome-Related Synovitis

Objectives: Synovitis plays an important role in knee osteoarthritis (KOA) pain. The activation of the NOD-like receptor protein 3 (NLRP3) inflammasome in fibroblast-like synoviocytes (FLSs) promotes KOA development. In this study, we aimed to investigate whether vanillic acid (VA), a monomer derive...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Zhenyuan, Huang, Zhengquan, Zhang, Li, Li, Xiaochen, Xu, Bo, Xiao, Yancheng, Shi, Xiaoqing, Zhang, Haosheng, Liao, Taiyang, Wang, Peimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917290/
https://www.ncbi.nlm.nih.gov/pubmed/33658936
http://dx.doi.org/10.3389/fphar.2020.599022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917290/
https://www.ncbi.nlm.nih.gov/pubmed/33658936
http://dx.doi.org/10.3389/fphar.2020.599022

Ejemplares similares