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Natural Compound α-PGG and Its Synthetic Derivative 6Cl-TGQ Alter Insulin Secretion: Evidence for Diminishing Glucose Uptake as a Mechanism

PURPOSE: Previously we showed that natural compound α-penta-galloyl-glucose (α-PGG) and its synthetic derivative 6-chloro-6-deoxy-1,2,3,4-tetra-O-galloyl-α-D-glucopyranose (6Cl-TGQ) act to improve insulin signaling in adipocytes by increasing glucose transport. In this study, we investigated the mec...

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Detalles Bibliográficos
Autores principales: Chen, Xiaozhuo, Daniels, Nigel A, Cottrill, David, Cao, Yanyang, Wang, Xuan, Li, Yunsheng, Shriwas, Pratik, Qian, Yanrong, Archer, Michael W, Whitticar, Nicholas B, Jahan, Ishrat, Nunemaker, Craig S, Guo, Aili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917315/
https://www.ncbi.nlm.nih.gov/pubmed/33658814
http://dx.doi.org/10.2147/DMSO.S284295