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Natural Compound α-PGG and Its Synthetic Derivative 6Cl-TGQ Alter Insulin Secretion: Evidence for Diminishing Glucose Uptake as a Mechanism
PURPOSE: Previously we showed that natural compound α-penta-galloyl-glucose (α-PGG) and its synthetic derivative 6-chloro-6-deoxy-1,2,3,4-tetra-O-galloyl-α-D-glucopyranose (6Cl-TGQ) act to improve insulin signaling in adipocytes by increasing glucose transport. In this study, we investigated the mec...
Autores principales: | Chen, Xiaozhuo, Daniels, Nigel A, Cottrill, David, Cao, Yanyang, Wang, Xuan, Li, Yunsheng, Shriwas, Pratik, Qian, Yanrong, Archer, Michael W, Whitticar, Nicholas B, Jahan, Ishrat, Nunemaker, Craig S, Guo, Aili |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917315/ https://www.ncbi.nlm.nih.gov/pubmed/33658814 http://dx.doi.org/10.2147/DMSO.S284295 |
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