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Dual Functional Eudragit(®) S100/L30D-55 and PLGA Colon-Targeted Nanoparticles of Iridoid Glycoside for Improved Treatment of Induced Ulcerative Colitis

AIM: Iridoid glycosides (IG) as the major active fraction of Syringa oblata Lindl. has a proven anti-inflammatory effect for ulcerative colitis (UC). However, its current commercial formulations are hampered by low bioavailability and unable to reach inflamed colon. To overcome the limitation, dual...

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Detalles Bibliográficos
Autores principales: Gao, Chenzhe, Yu, Shen, Zhang, Xiaonan, Dang, Yanxin, Han, Dan-dan, Liu, Xin, Han, Janchun, Hui, Mizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917316/
https://www.ncbi.nlm.nih.gov/pubmed/33658780
http://dx.doi.org/10.2147/IJN.S291090