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Dual Functional Eudragit(®) S100/L30D-55 and PLGA Colon-Targeted Nanoparticles of Iridoid Glycoside for Improved Treatment of Induced Ulcerative Colitis
AIM: Iridoid glycosides (IG) as the major active fraction of Syringa oblata Lindl. has a proven anti-inflammatory effect for ulcerative colitis (UC). However, its current commercial formulations are hampered by low bioavailability and unable to reach inflamed colon. To overcome the limitation, dual...
Autores principales: | Gao, Chenzhe, Yu, Shen, Zhang, Xiaonan, Dang, Yanxin, Han, Dan-dan, Liu, Xin, Han, Janchun, Hui, Mizhou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917316/ https://www.ncbi.nlm.nih.gov/pubmed/33658780 http://dx.doi.org/10.2147/IJN.S291090 |
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