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Lung expression of genes putatively involved in SARS-CoV-2 infection is modulated in cis by germline variants

Germline variants in genes involved in SARS-CoV-2 cell entry and in host innate immune responses to viruses may influence the susceptibility to infection. This study used whole-genome analyses of lung tissue to identify polymorphisms acting as expression quantitative trait loci (eQTLs) for 60 genes...

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Detalles Bibliográficos
Autores principales: Cotroneo, Chiara E., Mangano, Nunzia, Dragani, Tommaso A., Colombo, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917374/
https://www.ncbi.nlm.nih.gov/pubmed/33649539
http://dx.doi.org/10.1038/s41431-021-00831-y