AST-120 Improves Cardiac Dysfunction in Acute Kidney Injury Mice via Suppression of Apoptosis and Proinflammatory NF-κB/ICAM-1 Signaling

PURPOSE: Acute kidney injury (AKI) is a devastating disorder associated with considerably high morbidity and mortality. Reports have shown that AST-120, an oral charcoal adsorbent, can reduce oxidative stress by lowering serum indoxyl sulfate levels. The effects of AST-120 and indoxyl sulfate on kid...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Wen-Ching, Chou, Yu-Hsiang, Shi, Li-Shian, Chen, Zhi-wei, Tu, Hai-Jian, Lin, Xin-yi, Wang, Guei-Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917393/
https://www.ncbi.nlm.nih.gov/pubmed/33658826
http://dx.doi.org/10.2147/JIR.S283378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917393/
https://www.ncbi.nlm.nih.gov/pubmed/33658826
http://dx.doi.org/10.2147/JIR.S283378

Ejemplares similares