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AST-120 Improves Cardiac Dysfunction in Acute Kidney Injury Mice via Suppression of Apoptosis and Proinflammatory NF-κB/ICAM-1 Signaling

PURPOSE: Acute kidney injury (AKI) is a devastating disorder associated with considerably high morbidity and mortality. Reports have shown that AST-120, an oral charcoal adsorbent, can reduce oxidative stress by lowering serum indoxyl sulfate levels. The effects of AST-120 and indoxyl sulfate on kid...

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Detalles Bibliográficos
Autores principales:	Shen, Wen-Ching, Chou, Yu-Hsiang, Shi, Li-Shian, Chen, Zhi-wei, Tu, Hai-Jian, Lin, Xin-yi, Wang, Guei-Jane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917393/ https://www.ncbi.nlm.nih.gov/pubmed/33658826 http://dx.doi.org/10.2147/JIR.S283378

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